Women who are menopausal or affected with premature ovarian failure can now hope to become mothers with the use of oocyte donation and IVF. Here the uterus is primed for conception with estrogen and progesterone. The donor’s physical characters like skin color, height etc is matched with the recipient . IVF/ICSI is performed with the husband’s sperms and the donor eggs and embryos transferred to the recipient. 65% pregnancy rates per cycle can be expected with this technique.

Indications:

 Premature ovarian failure

 Turner syndrome

 Ovarian failure following chemotherapy or radiotherapy

 In vitro fertilisation failure

 Genetic disorders

Therapeutic insemination ( IUI ) with donor sperm

Males having absent or extremely low sperm count, who cannot afford ICSI or those with primary testicular failure, can opt for donor sperm from a semen bank. This remains one of the oldest ART methods known to mankind.

Indications:

 Severe male factor infertility ( Absent or low sperm counts, low sperm motility or sperm that requires surgical extraction due to prior vasectomy or other conditions)

 History of poor or abnormal fertilization

 High DNA fragmentation index

 Embryo development arrested in previous IVF cycle.

 Genetic disorder in male who are not pursuing preimplantation genetic diagnosis.

 Couples in which the male partner has an infectious disease, and the female partner does not.

 Single women, same-sex female couples and transgender individuals.