The retrieved embryonic cells are then sent for genetic analysis by the use of microchip method. In this a larger number of cells allow a more accurate genetic assessment of the embryo without affecting its further development.

Once the cells have been extracted from a blastocyst, the embryos are then frozen and stored for a few days until the genetic results are available.

The main limitation of the process of blastocyst biopsy is that usually only a limited number of embryos will reach the blastocyst stage. Therefore, the final decision on biopsy approach should be left to our experienced specialists.

Once the report of PGD / PGS has identified the embryos free of genetic problems, the embryo(s) will be transferred in the uterus in the next month (usually by an IVF procedure).

Any additional embryos that are free of genetic problems are kept frozen for possible later use while embryos with the problematic gene(s) are destroyed/ discarded.

The whole process can take several weeks/ months. If you think about it, this process includes collection, fertilization, 3-5 days of development, 1-2 weeks of testing, and scheduling an appointment to discuss results with your doctor. It is important to keep this in mind if you plan to pursue IVF with PGD/PGS so that you know what to expect!

Indications PGD

 Single gene disorders – Thalassemia, Duchenne Muscular Dystrophy

 Carriers of chromosome abnormalities – Translocation carriers

Indications PGS

 At risk for aneuploidy – maternal age > 35 yrs , Prior trisomic conception

 Recurrent pregnancy losses

 Failed IVF cycles – more than 3 prior embryo transfers with high quality, morphologically normal embryos.